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Over the last 50 years, drug development and clinical trials have resulted in successful complete responses in diseases such as childhood leukemia, ... More

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Understanding the role of hedgehog signaling in cancer is critically important for novel cancer therapeutics in humans. This volume provides ... More

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Summarizing the contribution that insertional mutagenesis has made to our understanding of cancer, this volume presents various insertional mutagens ... More

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Primary liver cancer is the third most deadly and fifth most common cancer worldwide (~500,000 deaths annually), with a sharp increase of incidence ... More

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David Fisher, MD, PhD, and an authoritative panel of academic, cutting-edge researchers review and summarize the current state of the field. ... More

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Oncogene-Directed Therapies captures the convergence between two areas in cancer research previously unexplored i.e. molecular oncology and cancer ... More

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Jointly authored by 89 distinguished medical, surgical and radiation oncologists from over 45 medical institutions throughout the United States, this ... More

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This book provides an overview of the Wnt pathway as a therapeutic target for cancer and discusses the preclinical development of inhibitors directed ... More

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The book describes most of the methods that are currently used in metastasis research. Both "in vivo" and "in vitro" protocols are illustrated, so ... More

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For this volume of Advances in Pharmacology we have brought together some of the foremost basic science and clinical researchers to discuss some of ... More

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The dreaded protozoal diseases caused by a number of Kinetoplastid parasites threaten mankind, as therapeutic tools for the treatment of most ... More

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Cancer genetics is a quickly growing field within oncology. The ability to identify individuals at high risk for cancer improves the chance of early ... More

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DNA topoisomerases represent an essential family of DNA processing enzymes and a large number of topoisomerase inhibitors are used clinically for the ... More

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The availability of new molecular approaches to the selection of drug therapy is an emerging need, as the traditional approach based on the ... More

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Chemokines are a superfamily of low molecular weight cytokines that were initially described based on their ability to induce the directed migration ... More

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Written by experts in the subject area, this timely book covers the molecular details and functional consequences of endocrine resistance in breast ... More

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