Internationally recognized scientists, clinicians, and technologists review and explain the fundamental molecular and cellular biology that has been applied to the emerging field of transplant immunology and xenotransplantation, and what impact these advances might optimally have on medicine and science. The authoritative experts writing here - ...
The use of animals as a source of cells, tissues, and organs for transplantation - xenotransplantation - has been of increasing interest in recent years. Transplantation of animal tissues into human patients is occurring now at various centers and the possibility of organ xenotransplants is widely discussed. This new volume presents a balanced ...
This text examines hyperacute xenograft rejection, a humoral immune reaction which destroys a vascularized organ graft within minutes to a few hours. The author summarizes classical concepts concerning the immunologic basis for hyperacute xenograft rejection, including the role of natural antibodies. Recent insights from pathogenesis are ...
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