The well-known persistence in the nosocomial environment of multidrug resistant bacterial and fungal species, today responsible for a wide variety of healthcare-associated infections, is believed to be greatly promoted by the ability of most of them to adhere and to grow in sessile mode on mucosal and soft tissues of hospitalized patients, as well as on the inner and outer surfaces of indwelling medical devices, including intravenous catheters, orthopaedic, cardiac valves, intrauterine devices, and contact lenses. In ...
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The well-known persistence in the nosocomial environment of multidrug resistant bacterial and fungal species, today responsible for a wide variety of healthcare-associated infections, is believed to be greatly promoted by the ability of most of them to adhere and to grow in sessile mode on mucosal and soft tissues of hospitalized patients, as well as on the inner and outer surfaces of indwelling medical devices, including intravenous catheters, orthopaedic, cardiac valves, intrauterine devices, and contact lenses. In this regard, a large number of these microorganisms, such as Acinetobacter baumannii, Candida albicans, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Staphylococcus aureus, give rise to highly organized, sessile community defined biofilms, in which microbes grow encased in a hydrated matrix of extracellular polymeric substances produced by themselves and are well protected from the attack of antimicrobial molecules and from the host immune response, by resisting phagocytosis and other body's defense systems. The great influence of the sessile growth on the effectiveness of the antibiotic therapies is due to both the structure and function of these microbial communities, making these also 1000 times more tolerant to antibiotics and disinfectants. Thus, alternative approaches to the common antibiotic treatments are emerging for preventing and treating both the mono-species and the most frequent multi-species biofilms, including enzymes able to disrupt mature biofilms and new biomaterials for the coating of medical devices to counteract microbial adhesion and biofilm formation. The aim of this Special Issue is to report on the state-of-art of the basic and applied research in the field of biofilm-based nosocomial infections that can be acquired by patients in both general hospitals and long-term care settings. Particularly, the involvement of microbial biofilms in medical device-related infections and other healthcare-associated infections, so far underestimated and/or scarcely investigated, has been considered, reviewed, and discussed.
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Add this copy of Biofilm-Based Nosocomial Infections to cart. $58.08, new condition, Sold by GreatBookPricesUK5 rated 5.0 out of 5 stars, ships from Castle Donington, DERBYSHIRE, UNITED KINGDOM, published 2015 by Mdpi AG.
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Fine. Sewn binding. Cloth over boards. 238 p. In Stock. 100% Money Back Guarantee. Brand New, Perfect Condition, allow 4-14 business days for standard shipping. To Alaska, Hawaii, U.S. protectorate, P.O. box, and APO/FPO addresses allow 4-28 business days for Standard shipping. No expedited shipping. All orders placed with expedited shipping will be cancelled. Over 3, 000, 000 happy customers.
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Fine. Sewn binding. Cloth over boards. 238 p. In Stock. 100% Money Back Guarantee. Brand New, Perfect Condition, allow 4-14 business days for standard shipping. To Alaska, Hawaii, U.S. protectorate, P.O. box, and APO/FPO addresses allow 4-28 business days for Standard shipping. No expedited shipping. All orders placed with expedited shipping will be cancelled. Over 3, 000, 000 happy customers.
Add this copy of Biofilm-Based Nosocomial Infections to cart. $76.11, new condition, Sold by GreatBookPrices rated 4.0 out of 5 stars, ships from Columbia, MD, UNITED STATES, published 2015 by Mdpi AG.
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New. Sewn binding. Cloth over boards. 238 p. In Stock. 100% Money Back Guarantee. Brand New, Perfect Condition, allow 4-14 business days for standard shipping. To Alaska, Hawaii, U.S. protectorate, P.O. box, and APO/FPO addresses allow 4-28 business days for Standard shipping. No expedited shipping. All orders placed with expedited shipping will be cancelled. Over 3, 000, 000 happy customers.
