Over the past five years the major importance of cytokines in the regulation of the immune system has become established. This book is the first to review the role of these factors in the control of the growth of differentiation of B-lymphocytes and thus represents an up-to-date and timely overview of the B-cell response. For the immunologist, there are detailed accounts of the physiochemical properties of the relevant cytokines and their effect on B-lymphocytes from the level of receptor signalling, through ontogeny, ...
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Over the past five years the major importance of cytokines in the regulation of the immune system has become established. This book is the first to review the role of these factors in the control of the growth of differentiation of B-lymphocytes and thus represents an up-to-date and timely overview of the B-cell response. For the immunologist, there are detailed accounts of the physiochemical properties of the relevant cytokines and their effect on B-lymphocytes from the level of receptor signalling, through ontogeny, activation and proliferation to hte expression of specific immunoglobulin isotypes. For the clinician, the involvement of cytokines in disease and normal immune response is discussed.
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