Thoroughly revised and updated, Optimization in Drug Discovery: In Vitro Methods, Second Edition presents a wide spectrum of in vitro assays including formulation, plasma binding, absorption and permeability, cytochrome P450 (CYP) and UDP-glucuronosyltransferases (UGT) metabolism, CYP inhibition and induction, drug transporters, drug-drug interactions via assessment of reactive metabolites, genotoxicity, and chemical and photo-mutagenicity assays. Written for the Methods in Pharmacology and Toxicology series, chapters ...
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Thoroughly revised and updated, Optimization in Drug Discovery: In Vitro Methods, Second Edition presents a wide spectrum of in vitro assays including formulation, plasma binding, absorption and permeability, cytochrome P450 (CYP) and UDP-glucuronosyltransferases (UGT) metabolism, CYP inhibition and induction, drug transporters, drug-drug interactions via assessment of reactive metabolites, genotoxicity, and chemical and photo-mutagenicity assays. Written for the Methods in Pharmacology and Toxicology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. Expert authors have developed and utilized these in vitro assays to achieve "drug-like" characteristics in addition to efficacy properties and good safety profiles of drug candidates. Comprehensive and up-to-date, Optimization in Drug Discovery: In Vitro Methods, Second Edition aims to guide researchers down the difficult path to successful drug discovery and development.
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Add this copy of Optimization in Drug Discovery: In Vitro Methods to cart. $158.36, new condition, Sold by Ingram Customer Returns Center rated 5.0 out of 5 stars, ships from NV, USA, published 2016 by Humana.
Edition:
2nd Softcover Reprint of the Original 2nd 2014 edition
Publisher:
Humana
Published:
2016
Language:
English
Alibris ID:
13546805715
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Add this copy of Optimization in Drug Discovery: In Vitro Methods to cart. $181.96, new condition, Sold by Ria Christie Books rated 5.0 out of 5 stars, ships from Uxbridge, MIDDLESEX, UNITED KINGDOM, published 2016 by Humana.
Edition:
2nd Softcover Reprint of the Original 2nd 2014 edition
Publisher:
Humana
Published:
2016
Language:
English
Alibris ID:
18937552976
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Standard Shipping: $4.87
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Seller's Description:
New. Trade paperback (US). Glued binding. 597 p. Contains: Unspecified, Illustrations, black & white, Illustrations, color, Tables, black & white. Methods in Pharmacology and Toxicology.
Add this copy of Optimization in Drug Discovery: In Vitro Methods to cart. $215.66, new condition, Sold by Ingram Customer Returns Center rated 5.0 out of 5 stars, ships from NV, USA, published 2013 by Humana.
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