"This important reference provides up-to-date information on all aspects of ribosome-inactivating proteins (RIPs). Including a list of all known RIPs, their distribution in nature, structure, genetics and chemical and immunological properties, this reference covers mechanisms of action, including the enzymatic activity on various polynucleotide substrates; the interaction with, and entry into cells; the toxicity to animals, including the pathology of poisoning; and the immunomodulatory and allergenic activity. The book ...
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"This important reference provides up-to-date information on all aspects of ribosome-inactivating proteins (RIPs). Including a list of all known RIPs, their distribution in nature, structure, genetics and chemical and immunological properties, this reference covers mechanisms of action, including the enzymatic activity on various polynucleotide substrates; the interaction with, and entry into cells; the toxicity to animals, including the pathology of poisoning; and the immunomodulatory and allergenic activity. The book further emphasizes the use of immunotoxins and other conjugates in clinical trials for the therapy of cancer and intractable pain"--
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Add this copy of Ribosome-Inactivating Proteins: Ricin and Related to cart. $126.95, very good condition, Sold by Flamingo Books rated 5.0 out of 5 stars, ships from Menifee, CA, UNITED STATES, published 2014 by Wiley-Blackwell.
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Very Good. Size: 6x0x9; 2014 signed and inscribed first edition, association copy (1977 Nobel winner Roger Guillemin), 7 x 9 7/8 inches tall color pictorial hardcover, no dust jacket (as issued), illustrated with color and black-and-white diagrams and drawings, index, xii, 296 pp. Laid in is a slip reading, 'From the Private Colllection of Dr. Roger and Lucienne Guillemin, Nobel Laureate, 1977, Salk Institute, La Jolla, CA. ' Roger Charles Louis Guillemin (1924-2024) was a French-American neuroscientist who received the National Medal of Science in 1976, and the Nobel Prize for Medicine in 1977 for his work on neurohormones. Very slight soiling, rubbing and edgewear to covers. On the title page, nicely signed by author Douglas Lappi and inscribed to Guillemin, widely considered the 'father of neuroendocrinology' and winner of the Nobel prize for medicine. Otherwise, a very good to near fine copy-clean, bright and unmarked. ~SP19~ [2.5P] This important reference provides information on all aspects of ribosome-inactivating proteins (RIPs). Including a list of all known RIPs, their distribution in nature, structure, genetics and chemical and immunological properties, this reference covers mechanisms of action, including the enzymatic activity on various polynucleotide substrates; the interaction with, and entry into cells; the toxicity to animals, including the pathology of poisoning; and the immunomodulatory and allergenic activity. The book further emphasizes the use of immunotoxins and other conjugates in clinical trials for the therapy of cancer and intractable pain. Contents: Preface; 1 Introduction and History; Introduction; Identification and Distribution in Nature; Mechanism of Action; Effects on Cells and Animals; Role in Nature; Practical Applications; Bioweapons; Future Challenges; References; 2 Occurrence and Taxonomical Distribution of Ribosome-inactivating Proteins Belonging to the Ricin/Shiga Toxin Superfamily; Introduction; How to Investigate the Distribution of Proteins with an N-glycosidase Domain? ; Conclusions; Acknowledgments. IntroductionFamily Sambuceae; Type 2 RIPs from Other families; Uses of nontoxic type 2 RIPs; Concluding remarks; Acknowledgment; References; 6 The Intracellular Journey of Type 2 Ribosome-inactivating Proteins; Introduction; Cell Surface Events; Endosome to TGN Sorting; From the Golgi to the ER; Reductive Separation and Destabilization of the Holotoxin Subunits; Dislocation Across the ERâ€0 embrane; Cytosolic Post-dislocation Events that Restore Catalytic Activity; Concluding Remarks; Acknowledgements; References. 7 Shiga ToxinsIntroduction; Purification of Shiga Toxins; Structure and Mechanism of Action of Shiga Toxins; Role of Shiga Toxins in the Pathogenesis of HUS; The 2011 German STEC Outbreak; References; 8 The Structure and Action of Ribosome-inactivating Proteins; Introduction; Acknowledgments; References; 9 Updated Model of the Molecular Evolution of RIP Genes; Introduction; Important Issues to be Considered in View of the Evolution of RIP Genes. Dissecting RIP Genes and RIP Gene Families by in silico Analysis of Genome and Transcriptome DataNew Insights in the Overall Phylogeny of Plant RIPs; An Updated Model of the Molecular Evolution of the Plant RIP Gene Family; What is the Evolutionary Link Between Plant and Non-Plant RIPs? ; Conclusions; References; 10 Enzymology of the Ribosome-inactivating Proteins; Introduction; Ricin as RNA N-glycosidase; Role of SRL in Ribosomes; Ribosomal RNA Apurinic Site-specific Lyase Intrinsic Stability of the Ribosomes; Action of RIPs on DNA.
Add this copy of Ribosome-Inactivating Proteins: Ricin and Related to cart. $138.18, like new condition, Sold by GreatBookPricesUK5 rated 5.0 out of 5 stars, ships from Castle Donington, DERBYSHIRE, UNITED KINGDOM, published 2014 by Wiley-Blackwell.
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Fine. Sewn binding. Paper over boards. 328 p. Contains: Illustrations, black & white, Line drawings, black & white, Tables, black & white, Figures. In Stock. 100% Money Back Guarantee. Brand New, Perfect Condition, allow 4-14 business days for standard shipping. To Alaska, Hawaii, U.S. protectorate, P.O. box, and APO/FPO addresses allow 4-28 business days for Standard shipping. No expedited shipping. All orders placed with expedited shipping will be cancelled. Over 3, 000, 000 happy customers.
Add this copy of Ribosome-Inactivating Proteins: Ricin and Related to cart. $141.84, like new condition, Sold by GreatBookPrices rated 4.0 out of 5 stars, ships from Columbia, MD, UNITED STATES, published 2014 by Wiley-Blackwell.
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Seller's Description:
Fine. Sewn binding. Paper over boards. 328 p. Contains: Illustrations, black & white, Line drawings, black & white, Tables, black & white, Figures. In Stock. 100% Money Back Guarantee. Brand New, Perfect Condition, allow 4-14 business days for standard shipping. To Alaska, Hawaii, U.S. protectorate, P.O. box, and APO/FPO addresses allow 4-28 business days for Standard shipping. No expedited shipping. All orders placed with expedited shipping will be cancelled. Over 3, 000, 000 happy customers.
Add this copy of Ribosome-Inactivating Proteins: Ricin and Related to cart. $156.10, new condition, Sold by GreatBookPrices rated 4.0 out of 5 stars, ships from Columbia, MD, UNITED STATES, published 2014 by Wiley-Blackwell.
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Seller's Description:
New. Sewn binding. Paper over boards. 328 p. Contains: Illustrations, black & white, Line drawings, black & white, Tables, black & white, Figures. In Stock. 100% Money Back Guarantee. Brand New, Perfect Condition, allow 4-14 business days for standard shipping. To Alaska, Hawaii, U.S. protectorate, P.O. box, and APO/FPO addresses allow 4-28 business days for Standard shipping. No expedited shipping. All orders placed with expedited shipping will be cancelled. Over 3, 000, 000 happy customers.
Add this copy of Ribosome-Inactivating Proteins Format: Hardcover to cart. $156.11, new condition, Sold by indoo rated 5.0 out of 5 stars, ships from Avenel, NJ, UNITED STATES, published 2014 by Wiley-Blackwell.
Add this copy of Ribosome-Inactivating Proteins to cart. $163.58, new condition, Sold by Educational Media Centre rated 4.0 out of 5 stars, ships from New Delhi, DELHI, INDIA, published 2014 by Wiley-Blackwell.
